USED AGILENT - KEYSIGHT 6550 IFUNNEL Q-TOF LC

The Agilent 6550 iFunnel Q-TOF LC/MS is a premium high-resolution accurate-mass (HRAM) mass spectrometry system designed for ultra-sensitive qualitative and quantitative analysis.

It incorporates Agilent iFunnel technology, which dramatically improves ion transmission efficiency, enabling femtogram-level sensitivity while maintaining high mass resolution and sub-ppm mass accuracy. The system is widely used in advanced research applications requiring precise compound identification in complex mixtures.

The instrument combines a quadrupole mass filter, collision cell, and time-of-flight analyzer, enabling both full-scan MS and MS/MS workflows for structural elucidation and trace-level detection.
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Key Highlights

- Ultra-sensitive iFunnel ion transmission technology for trace-level detection
- Femtogram-level sensitivity (one of the highest in LC-MS systems)
- High resolution up to ~40,000–45,000 FWHM (instrument dependent)
- Sub-ppm mass accuracy for confident compound identification
- Fast acquisition speeds up to 50 spectra/second
- Wide dynamic range (~5 orders of magnitude) for complex samples
- Dual Agilent Jet Stream ESI source for enhanced ionization
- Supports full scan, MS/MS, and data-independent acquisition (DIA)
- Integrated MassHunter software for advanced data processing
- Excellent performance for UHPLC coupling
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Applications / Uses

- Pharmaceutical drug discovery and development
- Metabolomics and proteomics
- Biomarker identification
- Food safety and contaminant analysis
- Environmental screening
- Forensic and toxicology analysis
- Complex mixture characterization
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Typical Specifications (Summary)

- Type: Quadrupole Time-of-Flight (Q-TOF) LC/MS
- Mass Range: ~m/z 20–10,000+
- Resolution: up to ~40K–45K FWHM
- Mass Accuracy: <1–2 ppm (typical)
- Ionization: ESI / AJS (Jet Stream)
- Scan Speed: up to 50 spectra/sec
- Dynamic Range: up to 10⁵
- Software: Agilent MassHunter suite
- LC Compatibility: Agilent 1290 Infinity / UHPLC systems
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Typical Configuration Includes

- 6550 Q-TOF mass spectrometer
- iFunnel ion source assembly
- Collision cell and quadrupole interface
- Vacuum system (turbo pumps)
- Data acquisition PC with MassHunter software
- LC interface module (UHPLC compatible)

Sameer Khanna

Sales Manager - BionexScientificUSA

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