USED SCIEX ZENOTOF® 7600

The SCIEX ZenoTOF 7600 is a next-generation high-resolution QTOF (Quadrupole Time-of-Flight) mass spectrometer designed for advanced qualitative and quantitative analysis in proteomics, metabolomics, and biopharmaceutical research.

It integrates two major innovations:

- Zeno Trap pulsing technology (boosts ion utilization and sensitivity)- Electron Activated Dissociation (EAD) for tunable fragmentation

This combination enables significantly improved MS/MS sensitivity (up to ~5–20× increase) and deeper structural characterization of complex molecules.

The system bridges the gap between high-resolution QTOF instruments and triple quadrupole sensitivity, allowing researchers to obtain richer structural data with high confidence.

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Key Highlights

- Advanced QTOF high-resolution mass spectrometer
- Zeno Trap technology → up to 5–20× sensitivity boost
- EAD fragmentation enables detailed structural analysis of biomolecules
- MS/MS scan speeds up to ~133 Hz
- Mass accuracy: <1–2 ppm RMS
- Resolution: ≥42,000 (at m/z ~956)
- Wide mass range: ~40 Da to 40 kDa
- Supports DDA, DIA (SWATH), and HR-MRM workflows
- Compact footprint compared to many HRMS systems
- Integrated SCIEX OS software for automation and data analysis
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Applications / Uses

- Proteomics (deep protein identification & PTM analysis)
- Metabolomics & lipidomics
- Biopharmaceutical characterization
- Structural elucidation of complex molecules
- Drug discovery and biomarker research
- Small molecule and impurity analysis
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Typical Specifications (Summary)

- System Type: QTOF LC-MS/MS system
- Ionization: ESI / APCI (Turbo V source options)
- Mass Range: ~40 – 40,000 m/z
- Resolution: ≥42k
- Mass Accuracy: <1–2 ppm
- Scan Speed: Up to 133 Hz
- Dynamic Range: >5 orders of magnitude
- Flow Range: ~5 µL/min to 3 mL/min (Turbo V source)
- Software: SCIEX OS, OneOmics Suite
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Typical Configuration Includes

- ZenoTOF 7600 MS main unit
- Ion source (Turbo V / OptiFlow options)
- LC system (often paired with ExionLC or microLC)
- Data acquisition workstation (SCIEX OS software)
- Calibration delivery system

Sameer Khanna

Sales Manager - BionexScientificUSA

(732) 672-5380Show moreShow lessClick to Request More Info

Type: Mass Spectrometers