USED AB SCIEX 4500

15-Day
Refurbishment cadence
OEM-Spec
Verified against OEM and published benchmarks; report included.
On-Staff
Solution Scientists
Since 1996
Three decades supporting labs
What you are buying
A refurbished SCIEX Triple Quad 4500 LC-MS/MS system. The liquid chromatograph front end separates the mixture and delivers it to the ion source. The source converts the eluent into gas-phase ions. The triple quadrupole isolates a precursor, fragments it, and measures the product ion for trace-level quantitation. GenTech rebuilds and tests the LC, the source, and the analyzer, then verifies the system end to end.
Every unit moves through the GenTech Certified process. Solution Scientists disassemble and inspect each module, replace all consumables and degraded wear components, then tune and calibrate the instrument and verify performance against OEM and published benchmarks using known reference chemicals. The instrument ships with its verification report. A certified-refurbished system gives you that performance without the capital cost or the lead time of a new purchase.
What Agilent says about this platform
SCIEX built the Triple Quad 4500 on the foundation of the API 4000 platform, re-engineering sensitivity, dynamic range, scan speed, and footprint. A Turbo V ion source with quick-change ESI and APCI probes handles a range of flow rates and compound classes. The Curtain Gas interface and QJet ion guide carry ions from the source into the analyzer. A Qurved LINAC collision cell fragments precursor ions for MS/MS. An AcQuRate pulse-counting detector, paired with a pulse overlap correction algorithm, counts ions for more accurate quantitation at high concentrations. eQ electronics drive fast scan speeds suited to UHPLC peak widths and short dwell times.
 
What each module does
Liquid chromatograph
Separates the mixture and delivers a reproducible gradient to the source. This listing does not specify a bundled HPLC brand; a compatible front end is sold separately or paired at the bench.
Ion source
A Turbo V source with quick-change ESI and APCI probes converts the liquid eluent into gas-phase ions across a range of flow rates.
Mass analyzer
Two quadrupoles flank a Qurved LINAC collision cell. The first selects a precursor, the cell fragments it, and the second measures a product ion for trace-level quantitation.
Vacuum and detection
Stages the ions from atmosphere to high vacuum, then counts them with an AcQuRate pulse-counting detector.
Technical detail
*OEM specifications for brand new instrument.
What “GenTech Certified” means
Refurbishment at GenTech is a defined process, not a wipe-down. Every system moves through the same five stages.
1. Disassembly and rebuild. Solution Scientists strip the instrument down, clean each module inside and out, and rebuild it from the frame up. They replace pump seals, pistons, and check valves to specification.
2. Configuration and new parts. Solution Scientists install the options and modules you selected and fit new wear parts throughout. They replace the detector lamp with a new one and reset the lamp hours.
3. Diagnostic and performance testing. Solution Scientists tune and calibrate the instrument, run system diagnostics, and confirm detector wavelength accuracy. They test full-system pressure and gradient performance against OEM and published benchmarks using known reference chemicals.
4. Data package you approve before shipment. The verification data goes to you for approval before the system leaves the bench. You see exactly how the instrument performs before it ships.
5. Delivery and installation. The instrument ships in protective packing with a one-year warranty option and professional installation available from a GenTech Solution Scientist.
Labs that run this system
The AB Sciex QTrap 4500 is method-compatible across the techniques most regulated and research labs run every day. These are the application areas buyers ask about most.
PFAS testing
EPA Method 537.1 and similar state programs require quantitation of per- and polyfluoroalkyl substances in drinking water at low parts-per-trillion levels, a sensitivity range triple quadrupole MS is built to reach.
Pesticides and mycotoxins
Multi-residue pesticide panels and mycotoxin screens in food and cannabis testing often cover more than 100 compounds in a single run, each requiring the selectivity a triple quadrupole provides against a complex matrix background.
Trace impurities and cleaning validation
Pharmaceutical cleaning validation protocols confirm that equipment surfaces carry no detectable residue of the previous product, often down to sub-part-per-billion swab or rinse limits.
Quantitative toxicology
Forensic and clinical toxicology panels quantify drugs and metabolites in blood, urine, or tissue against legally defensible limits, where a triple quadrupole’s selectivity rules out false positives from matrix interferences.
GLP-grade quantitation
Good Laboratory Practice studies require documented, audit-ready quantitation with full method validation, a standard regulated bioanalysis labs run routinely on triple quadrupole platforms.
Additional Information
Documentation
Financing

Sciex 4500 Series User Guide
Financing Options Available.  Finance Builder.
Need a main board instead?
Replacing a failed pump or looking to upgrade your mass spec? Every module in this system is available individually, in stock and performance-verified.
[In this stack]
SCIEX Triple Quad 4500 Triple Quad 4500: Verified
1260 Vialsampler G7129A: Verified
1260 Multicolumn Thermostat G7116A: Verified
1260 Diode Array Detector G7115A: Verified
Workstation loaded with software: Included
[Each module is individually serialized and performance-verified before the stack is assembled and tested as a complete system.]
Analyzer: Triple quadrupole
Ion source: Turbo V, quick-change ESI/APCI probes
Collision cell: Qurved LINAC
Detector: AcQuRate pulse-counting
Ion guide / interface: QJet, Curtain Gas
Weight: 350 lbs
Dimensions: 60 × 60 × 60 in
OEM: AB Sciex
Model: 4500
Condition: Refurbished
Financing: Financing Options Available