USED AAPPTEC TITAN 357

The AAPPTec Titan 357 Automated Combinatorial Peptide Synthesizer is a high-throughput solid-phase peptide synthesis (SPPS) platform designed for split-and-combine combinatorial peptide library generation, parallel peptide synthesis, and scale-up peptide production. The system automates peptide synthesis using dual robotic arms for precise reagent delivery and resin transfer, enabling researchers to efficiently generate peptide libraries containing thousands to millions of compounds.

The Titan 357 can operate in three modes: split-and-combine library synthesis, parallel synthesis of up to 36 individual peptides, or large-scale single peptide synthesis using its 500 mL reaction vessel. It is widely used in pharmaceutical research, drug discovery, medicinal chemistry, epitope mapping, and peptide screening.

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Key Highlights

- Automated solid-phase peptide synthesizer (SPPS)
- Split-and-combine combinatorial peptide library synthesis
- Parallel synthesis of up to 36 peptides simultaneously
- Large 500 mL scale-up reaction vessel
- Dual robotic arms for reagent delivery and resin transfer
- Variable-speed vortex mixing
- Nitrogen bubbling for efficient mixing
- User-programmable synthesis protocols
- Supports randomized and custom peptide libraries
- Designed for high-throughput peptide discovery and research
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Applications / Uses

- Peptide library synthesis
- Drug discovery
- Combinatorial chemistry
- Epitope mapping
- Peptide screening
- Medicinal chemistry
- Protein interaction studies
- Biomarker research
- Academic research
- Pharmaceutical R&D
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Typical Specifications (Summary)

- Instrument Type: Automated Peptide Synthesizer
- Synthesis Method: Solid Phase Peptide Synthesis (SPPS)
- Modes of Operation:Split-and-combine synthesis
- Parallel peptide synthesis
- Scale-up peptide synthesis
- Parallel Reactors: 36 × 10 mL
- Main Reactor: 500 mL
- Mixing: Variable-speed vortex mixing and nitrogen bubbling
- Robotic System: Dual robotic arms
- Library Capacity: Thousands to millions of peptide compounds
- Control: PC-based programmable software
- Chemistry: Fmoc-based peptide synthesis (compatible with standard SPPS protocols)
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Typical Configuration Includes

- AAPPTec Titan 357 synthesizer
- Dual robotic arm assembly
- 36-position reactor assembly
- 500 mL reaction vessel
- Reagent delivery system
- Resin transfer system
- Control computer and software
- Tubing and fittings
- Power cable
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