USED NOVASEP PROCHROM 80

The Novasep Prochrom® 80 is a Dynamic Axial Compression (DAC) preparative chromatography column engineered for pilot-scale and production-scale purification of biologics, pharmaceuticals, peptides, proteins, antibodies, and other high-value compounds. The column utilizes hydraulically actuated Dynamic Axial Compression (DAC) technology to maintain constant compression of the chromatography bed throughout operation, ensuring excellent packing stability, high separation efficiency, and reproducible purification performance. The Prochrom platform is recognized for its durability, with many systems remaining in production service for decades.

The Prochrom 80 features an 80 mm internal diameter and is commonly used for process development, pilot production, and intermediate manufacturing. Depending on the specific configuration, it supports operating pressures up to 100 bar and adjustable bed heights for a wide range of chromatographic media and purification processes.

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Key Highlights

- Dynamic Axial Compression (DAC) technology
- 80 mm internal diameter preparative chromatography column
- Adjustable packed bed height
- Hydraulically actuated compression piston
- Stainless-steel construction
- Excellent bed stability and packing reproducibility
- Supports pilot and production-scale purification
- Compatible with most chromatography resins
- Fast packing and unpacking (typically 15–30 minutes)
- Designed for decades of continuous industrial operation
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Applications / Uses

- Monoclonal antibody purification
- Recombinant protein purification
- Vaccine manufacturing
- Peptide purification
- API purification
- Affinity chromatography
- Ion exchange chromatography
- Hydrophobic interaction chromatography (HIC)
- Size exclusion chromatography (SEC)
- Biopharmaceutical downstream processing
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Typical Specifications (Summary)

- Column Type: Dynamic Axial Compression (DAC)
- Internal Diameter: 80 mm
- Bed Height: Approximately 350–450 mm (configuration dependent)
- Maximum Operating Pressure: Up to 100 bar
- Compression System: Hydraulic DAC piston
- Construction: 316L Stainless Steel
- Temperature Control: Optional thermostated jacket
- Typical Flow Rate: 15–30 L/hour (application dependent)
- Compatible Media: Agarose, silica, polymeric, ion exchange, affinity, HIC, SEC resins
- Applications: Preparative HPLC and process chromatography
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Typical Configuration Includes

- Novasep Prochrom 80 chromatography column
- Hydraulic DAC piston assembly
- Stainless-steel column body
- Adjustable bed assembly
- Column stand with casters
- Tubing connectionsShow moreShow lessClick to Request More Info