USED KBIOTECH GMBH BIOBOOK MODULAR BIOREACTOR

The KBiotech BioBook™ Modular Bioreactor is a highly configurable benchtop bioreactor and fermenter platform designed for research, process development, and pilot-scale bioprocessing. Built around a modular architecture, the system supports glass, stainless steel, single-use, air-lift, and photobioreactor vessels with working volumes ranging from 50 mL to 20 L on a common control platform.

Powered by Smart-BioFlex™ control software, the BioBook platform offers advanced process automation, real-time monitoring, recipe management, audit trails, and optional 21 CFR Part 11 compliance. The modular design allows users to expand from a single reactor to twin or parallel configurations while maintaining the same control environment, making it ideal for microbial fermentation, mammalian cell culture, vaccine development, and biopharmaceutical process optimization.

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Key Highlights

- Modular benchtop bioreactor platform
- Working volumes from 50 mL to 20 L
- Compatible with glass, stainless steel, single-use, and photobioreactor vessels
- Smart-BioFlex™ automation software
- Optional 21 CFR Part 11 compliance
- Real-time control of pH, DO, temperature, foam, and level
- Multiple gas mass flow controllers (MFCs)
- Multiple peristaltic pumps for feeding and dosing
- Supports batch, fed-batch, and perfusion processes
- Inline PAT integration (Raman, biomass, off-gas, metabolites)
- Remote monitoring and LIMS/SCADA integration
- Expandable to twin and parallel reactor configurations
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Applications / Uses

- Microbial fermentation
- Mammalian cell culture
- Vaccine development
- Biopharmaceutical process development
- Cell and gene therapy research
- Synthetic biology
- Protein expression
- Process optimization
- Academic research
- Pilot-scale bioprocess development
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Typical Specifications (Summary)

- Instrument Type: Modular Benchtop Bioreactor/Fermenter
- Working Volume: 50 mL–20 L
- Vessel Types: Glass, stainless steel, single-use, air-lift, photobioreactor
- Temperature Control: 2–80°C
- Temperature Accuracy: ±0.1°C
- pH Range: 0–14
- DO Range: 0–300%
- Gas Control: Up to 5–8 mass flow controllers
- Feed Pumps: Up to 4–8 peristaltic pumps
- Process Modes: Batch, fed-batch, perfusion, continuous
- Software: Smart-BioFlex™
- Connectivity: OPC UA, REST API, SCADA/MES, LIMS integration
- Compliance: Optional 21 CFR Part 11, GMP-ready configuration
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Typical Configuration Includes

- BioBook modular control unit
- Benchtop bioreactor vessel
- Agitation drive
- Temperature control module
- pH and DO sensors
- Peristaltic pump module
- Gas mixing module
- Smart-BioFlex™ software
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